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Antimicrobial Additives for Medical Devices

The antimicrobial additives for medical devices is an advanced controlled release antimicrobial treatment for wound dressings, bandages, and various medical devices.

ZeoVation’s smart particle antimicrobial is used to help prevent infection and protect from common infectious bacteria and other contaminants.

The value proposition that has motivated the development of our antimicrobial is the proliferation of antibiotic-resistant bacteria and the dramatic fall in the number of antibiotics in development.

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wound care equipment
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wound care

What are the Benefits of the Antimicrobial for Medical Devices?

The antimicrobial has been developed with extensive consideration given to product performance. It helps to:

  • Resist bacterial colonization within the dressing
  • Reduce bacterial penetration through the dressing
  • Provide protection against gram-, gram+ and fungi/yeast microorganisms
  • Limits cross-contamination from and to the patient, clinician, and environment
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The Effectiveness 

Our controlled-release antimicrobial is effective against gram-positive, and gram-negative bacteria (including methicillin-and vancomycin-resistant bacteria) as well as fungi and viruses. 

With significantly higher potency, it requires lower antimicrobial dosages, a lower environmental footprint, and lower non-bacterial cellular interactions. The key features of our antimicrobial are:

  • An enormous increase in surface area results in more coverage with lesser particle amounts. That is a 1000x increase in surface area coverage compared to micron-sized particles
  • Faster, more efficient ion exchange due to the shorter distance the molecules have to travel
  • Ability to penetrate and destroy bacteria from the inside out

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Test Results for FRAg (fast release) and SRAg (slow release)


wound care graph

7 to 8 log reduction of bacteria counts (CFU/ml)

wound care graph


Testing Notes:
  • Substrate: 30-40 nm transparent, dispersible NZ crystals (agglomerate size controlled from colloidal meters to microns)
  • Conditions for antimicrobial testing: E.coli, FRAg, SRAg = 100 µg/ml, 37 °C, 75 min
  • MIC (MBC) of FRAg 1.56 micrograms/ml; SRAg 3.125 micrograms/ml (positive control ampicillin 0.5 micrograms/ml) towards E.coli (2.5×104 CFU/ml)

Product Information

Product Type:Powder or Dispersion
Product Name:FRAg [Fast release] or SRAg [Slow release]
Particle Size:30 nm to micron-size aggregates

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